🔊 Breakthrough: Scientists 3D Print Medical Implants INSIDE the Body Using Ultrasound!

A team from Caltech has developed "DISP" (Deep Tissue In Vivo Sound Printing)—a revolutionary method to 3D print hydrogels directly inside organs and tissues using ultrasound.

⚡ How It Works

  1. Bioink Injection: A specialized liquid (polymer + crosslinkers) is injected.

  2. Ultrasound Activation: Focused ultrasound heats lipid particles to 41.7°C, releasing crosslinkers to form solid hydrogels.

  3. Precision Printing: Complex shapes (stars, teardrops) can be printed 4cm deep—reaching muscles, organs, and tumors.

💊 Potential Applications

  • Targeted Drug Delivery: Slow-release chemo hydrogels killed more cancer cells than injections in lab tests.

  • Tissue Repair: Printed artificial tissue accelerated healing in rabbits.

  • Implantable Sensors: Conductive inks (carbon nanotubes) could monitor heart rhythms.

Quote from Dr. Wei Gao (Caltech):
"Unlike light-based methods, ultrasound reaches deep tissue. This could someday mean printing bandages inside a beating heart."

🚀 Next Steps

  • Testing in larger animals → human trials.

  • AI integration for printing in moving organs (e.g., heart).

#MedTech #3DPrinting #CancerTreatment #Biotech #ScienceInnovation

Reference
Davoodi E et al. Imaging guided deep tissue in vivo sound printing, Science, 388, 6747, 616-623 (2025).

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